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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Zebrafish phenotyping platform

Zebrafish phenotyping platform

The Zebrafish phenotyping platform aims at producing in vivo models for the study of infectiology and immunity using zebrafish as a model organism.
Created in 2012 in INRAE, this experimental installation support imaging experiments for reserachers,  being part of the Infectiology of fish and rodent experimenal unit (IERP Unit) and belonging to the EMERG’IN Research infrastructure for the control of animal and zoonotic emerging infectious diseases through in vivo investigation.
The platform allows INRAE researchers and more broadly the national and international scientific community to benefit from the facilitie and expertise for:
--> Performing infectology experiments under controlled conditions associated with high resolution phenotyping, Screening of therapeutic molecules targeting animal or human health diseases.
--> 3D Imaging of whole organisms based on adavanced tissue clearing methods.
--> Technological research and development related to fish phenotyping and nanotchnology.
Ideally located in the BSL2 zone of the fish facility, the phenotyping platform provides an optimal environemnt to conduct live imaging of pathogen infections (viruses, bacteria, prions) and host responses through infection of zebrafish transgenic lines available in the structure. 


EAAP webinar series

EAAP webinar series

december 14th e-conference

Contribution and application of the Zebrafish model to the "One Health" concept.

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 Apports des techniques d'imagerie en trois dimensions pour l'étude des interactions hôtes-pathogènes

Apports des techniques d'imagerie en trois dimensions pour l'étude des interactions hôtes-pathogènes

Apports des techniques d'imagerie en trois dimensions pour l'étude in vivo/ ex vivo des interactions hôtes-pathogènes
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Imaging viruses : from single molecule to diagnosis

Imaging viruses : from single molecule to diagnosis

Recent advances in photonic micro/nanoscopy and AFM applied to virology. March 16, 2021
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cGAS: structure, function and evolution from bacteria to metazoa

A review on the current knowledge about cGAS: structure, function and evolution from bacteria to metazoa

Conservation of cGAS-STING pathway : a universal therapeutic target to fight against animal and human infectious diseases.
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