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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Institutions

SPS - Saclay Plant Sciences

Functional relationships between thioredoxins and mitogen-activated protein kinases in plants (TRX&MAPK)

Coordinator: Emmanuelle Issakidis-Bourguet / Jean Colcombet

PhD project selected in 2013 – Person recruited: Cécile Sozen

The sessile condition of plants exposes them continuously to any environmental stress. Injury, one of the most frequent stress conditions that plants must face may cause harsh damages to the plant tissues and facilitate the entry of pathogens. Therefore, plants have evolved mechanisms to respond efficiently to wounding by healing the damaged tissues and preventing the pathogen infection. Environmental stresses are perceived by specific receptors which activate signaling pathways leading to those responses. Mitogen-Activated Protein Kinases modules consisting of 3 kinases (MAP3K, MAP2K and MAPK) activated in cascade represent an important signaling pathway involved in response to various biotic and abiotic stresses. The role of MAPKs in response to wounding is slowly emerging. The aim of this project is to identify the place of a patricular MAP2Kin the wound-induced response by identifying the upstream signals and the cellular responses triggered by this pathway (gene expression, resistance to pathogen, etc.). Our results allowed us to identify a new complete module activated by wounding. In addition, we identified jasmonic acid, an phytohormone produced upon wounding, as an important actor acting upstream our MAPK module. Nevertheless, the role of our module in plants responses to wounding remains to be determined.