François Parcy

François Parcy - 08/11/2022

How does LEAFY make flowers and cauliflowers

08 novembre 2022

IPS2 et en ligne

François Parcy (Laboratoire Physiologie Cellulaire & Végétale (LPCV), Grenoble, France)

The LEAFY (LFY) gene is a key actor of flower morphogenesis in angiosperms. It controls various facets of flower meristem development from the meristem emergence to its identity and patterning. This gene encodes a plant specific transcription factor (TF) for which we study the function, the structure and the evolution. I will present recent results dealing with 1) the role of LFY in the morphogenesis of the cauliflower forms. This work (Azpeitia Science 2021) is a combination of modelling and molecular genetics showing how perturbation of the floral network can yield new shapes. 2) The way the F-box protein UFO acts as a LFY partner to change its DNA binding specificity and target gene repertoire (Rieu, Biorxiv 2022). This work combines molecular genetics, computational biology and structural biology to answer a developmental question (the floral meristem patterning). It illustrates how a non-TF protein can drastically change the properties of a master regulator and allow tissue-specific gene regulation.

 

Contact: marie-jeanne.sellier@inrae.fr

Date de modification : 06 décembre 2023 | Date de création : 28 novembre 2023