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Dernière mise à jour : Mai 2018

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Decrease the prevalence of Salmonella carrier state in animals : a multidisciplinary approach

INRA Prod. Anim., 21(1), 117-126.


1 INRA, UR1282 Infectiologie Animale et Santé Publique, F-37380 Nouzilly, France
2 INRA, ENVN Atlanpole, UMR1300 Bioagression, Epidémiologie et analyse de risques, F-44307 Nantes, France
3 AFSSA, Hygiène et Qualité des Produits Avicoles et Porcins, Zoopôle Beaucemaine, F-22440 Ploufragan, France
4 INRA, UR444 Génétique Cellulaire, F-31326 Castanet-Tolosan France
5 INRA, UR83 Recherches Avicoles, F-37380 Nouzilly, France


Most human cases of salmonellosis in developed countries are related to the consumption of contaminated eggs, poultry and pig meat. To improve food safety, INRA aims, in collaboration with AFSSA, at decreasing the prevalence of contamination of raw animal material, especially those originating from poultry or pigs. This implies improving animal health and reducing asymptomatic carrier-state (i.e animals carrying or shedding bacteria without any clinical signs). This involves increasing the knowledge of mechanisms of animal colonisation by bacteria and also the immune response allowing the host to resist the pathogen. These studies will result in the development of vaccines and drugs but also in the selection of animals more resistant to the Salmonella carrier state. Finally, an integrative approach, using results from experiments and field studies, allows modelising the contamination of animals and food industries and in turn evaluating the risk of transmission and the impact of prophylactic means.

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