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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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How INRA has organised observations and experimentation on model or farm animals infected by transmissible spongiform encephalopathy

Inra Prod. Anim., 2004, Numéro hors série, 7-12


1 INRA, Station d’Amélioration Génétique des Animaux, Chemin de Borde-Rouge–Auzeville, BP 27, F-31326 Castanet-Tolosan Cedex

2 INRA, Pathologie Infectieuse et Immunologie, BP 2, F-37380 Nouzilly

3 INRA, Virologie et Immunologie Moléculaires, Domaine de Vilvert, F-78350 Jouy-en-Josas

4 INRA, Domaine de Langlade, Pompertuzat, F-31450 Montgiscard

5 ENVT, Interactions hôte-agents pathogènes, 23 chemin des Capelles, F-31076 Toulouse Cedex 3

6 INRA, LABOGENA, Centre de Recherche de Jouy, F-78352 Jouy-en-Josas


The investments at INRA for the study of transmissible spongiform encephalopathy (TSE) in animal populations, on farms or in experimental conditions are described : a large scale PrP gene genotyping laboratory, the experimental farm of Langlade where sheep submitted to natural scrapie are followed, an important protected animal building (Installations Nationales Protégées pour l’étude des Encéphalopathies Spongiformes Transmissibles “INPREST”) for large farm animals, the sheep house of the Toulouse National Veterinary School (ENVT), the protected rodent buildings on the INRA sites of Nouzilly and Jouy-en-Josas and Toulouse (ENVT). All these investments give scientists the means necessary to carry out their investigations on the physiopathology of animal TSE, the genetic determinants of the sensitivity/ resistance of these pathologies, the nature of the pathogenic agent and notably its variability as well as the evaluation of risks and the diagnostic.

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