Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal

Home page

Control of oxidative phenomenon during gestation in monogastrics and ruminants

INRA Prod. Anim. 17(5), 339-354.

B. AUROUSSEAU, D. DURAND, D. GRUFFAT

INRA, Unité de Recherches sur les Herbivores, F-63122 St-Genès-Champanelle

Abstract 

In mammals, radical chains are necessary to support cell replication, differentiation and growth, as well as metabolic activity of different cell types. They have a very important effect in the course of gestation. The high metabolic rate of the uterus and conceptus (placenta and embryo), favoured by oestrogen secretion during this period of a mammals’ life, increases production of oxygen free radicals at different cellular locations, namely the mitochondria. They play a role in membrane fusion, which allows nidation of the embryon and remodelling of the uterine, placental and embryonic tissues, in the development of new blood vessel characteristics of gestation, settlement of cotyledons and the increase in membrane permeability, which allows an intensive influx of nutrients required by foetus development. Vitamins and minerals from the body stores of the gestating female are involved in preventing an unbalance between production and scavenging of oxygen free radicals (oxidative stress), which would lead to alterations of the organisms of the mother and foetus. Part of the vitamins is destroyed in the course of free radical trapping and part of the minerals is lost when the enzymes to which they are linked are inactivated by free radicals. The requirements of gestating females are therefore increased. Adaptation of the alimentary inputs must not only face these increased requirements, but also increases linked to the exposure to numerous stresses during their life, namely climatic stress. The latter decreases, in particular, cobalt content in the forages, and thus, lowers the synthesis in the rumen of vitamins B12 and B9 (folic acid), which are critical for the integrity of the maternal organism, for the development of the foetus, and for the achievement of gestation. Improvements of knowledge on these very scarcely studied aspects are necessary to promote a long lasting stable agricultural system of production.

Download documents