Dissemination in International Scientific Conferences

Conferences / Oral communications of POSITIVe members on the topic of the Action:

19th world congress of Food Science & Technology (IUFoST), October 23-27, 2018, Mumbaï, India
Inter-individual variation in the bioavailability and bioefficacy of dietary plant food bioactives in humans
C. Morand (Chair)

Final Conference COST Action POSITIVe, 25-26 October 2018, Lisbon, Portugal
Session : Main Findings from POSITIVe :

• Determinants of interindividual variability in absorption, distribution, metabolism and excretion of plant food bioactives – T. van de Wiele (WG1)
• Carotene in Humans – Metabolic Pathway and Bioactivation - from Digestion to Tissue Distribution and Excretion - T. Bohn (WG1)
• Microbiome variants in relation to bioavailability of plant food bioactives -  K. Tuohy (WG1)
• Untargeted metabolomics for assessment of true exposure to plant food bioactives – C. Manach (WG1)
• Quality of reporting of clinical trials addressing the inter-individual variation in response to plant bioactives -  A. Konic-Ristic (TTG, WG2)
• Investigating variability in cardiometabolic response to plant food bioactives: approaches and main findings from POSITIVe – A. Rodriguez-Mateos (WG2)
• Evaluation of cell and molecular targets of plant food bioactives: implications for inter-individual variability - D. Milenkovic (WG2)
• Impact of gut microbial metabolism on cardiometabolic markers - F. Tomas-Barberan (WG1&2)
• Beyond results - lessons learned from POSITIVe meta analyses – E. Combet (WG2)

 
2^nd International Conference on Food Bioactives and Health, Lisbon (Portugal), 26-28 Octeober, 2018.

• Gene Expression Analyses in Human Tissues in Response to Dietary Bioactive Compounds: a Critical Review. M.T. García-Conesa (WG2)
• Gold standards for a realistic polyphenol research. Pedro Mena (WG1&2)
• Urolithins and equol: similar bioactive gut microbiota metabolites with different food origin. Francisco Tomás Barberán (WG1&2)
• The role of dietary bioactives in lifelong health – what works for whom? B. de Roos (WG3) conference
• Biotransformation of silymarin flavonolignans by human fecal microflora. K. Valentova et al, (WG1)

Bioavailability 2018 Conferences, Norwich, UK, 09/2018
Host-related factors explaining individual variation in carotenoid bioavailability’, T. Bohn (WG1)

BON Conference, Cambridge, UK, 06/2018
Carotenoid Bioavailability–Knowns and Unknowns’, T. Bohn (WG1)

Wageningen University, Food4Future event (June 2018).
A HEALTHY DIET - But what works for me personally? B. Roos (WG3)

Nutritigenomics Summer School, Jesi, Italy (June 2018),
New insights into nutritional blood biomarkers. B. de Roos (WG3)
 
Carotenoid bioavailability training school, 19-23 March 2018, Newcastle (UK).
Genetic variation analysis - a step by step practical guide. C. Desmarchelier (WG1)
The effect of genetic variations on the bioavailability of carotenoids in humans. C. Desmarchelier (WG1)

8^th international Conference on Polyphenols and Health, October 3-6,  2017, Quebec city, Canada.
Substantial variability across individuals in the vascular and nutrigenomic response to an acute intake of curcumin: A randomised controlled trial. C. Morand (chair)

Precision Nutrition Conference, Shanghai, China (November 2017)
Personalised Interventions - A precision approach for the next generation of dietary intervention studies. Baukje de Roos (WG3) 

3^rd Scientific Workshop of POSITIVe, 20-21 September 2017, Thessaloniki, Greece.

• Biomarkers of food intake and effect after consumption of plant-based dietary patterns in cardiovascular risk participants. Mireia Urpi-Sarda (TTG, WG2)
• The impact of genotype on the metabolism and bio-efficacy of plant polyphenols. Anne Marie Minihane (WG2)
• Gene expression profiling in whole blood cells from healthy men after chronic blueberry consumption. Geoffrey Istas (TTG, WG2)
• Systems biology characterization of immunomodulatory properties of Echinacea in monocyte cells. Ken Declerck (WG2)
• Individuality in the gut microbiota determines rutin metabolism. David Berry (WG1)

2^nd Scientific Workshop of POSITIVe at the International conference on Food Bioactives ansd Health (13-15 October 2016), Norwich, UK

• Variability in the biological responsiveness of plant food bioactives regarding cardiometabolic endpoints. Ana Rodriguez-Matéos (WG2)
• Interindividual variability in the absorption, distribution, metabolism and excretion of plant food bioactives. Tom Van de Wiele (WG1)
• Urolithin metabotype clustering determines the effect of pomegranate consumption on lipid cardiometabolic biomarkers. Evidence from a double-blind, cross-over, dose-response, randomized, placebo-controlled trial. González-Sarrías A et al (TTG, WG2)
• Intra- and inter-individual variation in urinary excretion of metabolites of phenolic acids after consumption of coffee. Williamson G (WG1)
• Acute intake of curcumin differently affects endothelial function and nutrigenomic response in male and female smokers: a randomized controlled trial. Milenkovic D et al (WG2)
• Inter-individual variability in response to the intake of flavonols on blood lipid levels:a meta-analysis of randomized controlled human trials. Pinto P et al, (WG2)
• Effect of a Functional Fruit Concentrate on post-prandial glycaemic response in pre-diabetes and type 2 diabetes patients: exploring the inter-individual variation. Bronze M, (WG2)
• Inter-individual variability in the combined production of metabolites from green tea flavan-3-ols and coffee chlorogenic. Mena P, (TTG, WG1)

1^st Scientific Workshop of POSITIVe in Satellite to 7th ICPH, 26-27 October 2015, Tours, France.

• Introduction of the COST Action POSITIVe. C. Morand (chair)
• Interindividual differences in polyphenols gut microbiota metabolism. Can they affect human health?  F.A. Tomás-Barberán (co-chair)
• Single nucleotide polymorphisms associated with carotenoid bioavailability. P. Borel (WG1)
• Variation in vascular response to cocoa flavanol intake according to age and sex. A. Rodríguez-Mateos (WG2)
• From inflammaging to healthy aging: is epigenetics the key to personalized medicine or dietary health recommendations? W. Vanden Berghe (WG2)
• From pathways to networks:  A cofactor-protein interactome as a model for plant bioactive, J. kaput (WG2)
• Food4Me and personalised nutrition. E. Gibney (WG3)

4^th International Conference of Food Digestion (ICFD)March 17-19th, 2015, Naples, Italy.
Interindividual variation in response to consumption of plant food bioactives and determinants involved - Objectives of the COST action POSITIVe. C. Morand (chair)
 

Posters of POSITIVe members on the topic of the Action:
 

1^st Nordic Metabolomics Conference, Örebro, Sweden, August 26–28, 2018
Interlaboratory Coverage Test on Plant Food Bioactive Compounds and their Metabolites by MS-Based Untargeted Metabolomics.
Koistinen VM, Bento da Silva A, Abrankó L, Low D, Garcia Villalba R, Tomás Barberán F, Landberg R, Savolainen O, Alvarez-Acero I, de Pascual-Teresa S, Van Poucke C, Almeida C, Petrásková L, Valentová K, Durand S, Wiczkowski W, Szawara-Nowak D, González-Domínguez R, Llorach R, Andrés-Lacueva C, Aura A-M, Seppänen-Laakso T, Hanhineva K, Manach C, Bronze MR (WG1)

2^nd International Conference on Food Bioactives and Health, Lisbon (Portugal), 26-28, 2018.

• Impact of (poly)phenol consumption in diabetic patients: a meta-analysis of randomized controlled human trials. Ana F Raimundo, Regina Menezes,  Filipa Félix, Ana Raimundo, Ana Rodriguez-Mateos, Antonio González-Sarrías, Brian Wang, Claudia Santos, Dulce do Ó, Ana Silva, João VG Lopes, Manuel Schär, María-Teresa García-Conesa, Rita Andrade, Rogério Ribeiro,Paula Pinto (WG2).
• Impact of cocoa and tea flavanols on blood pressure and endothelial function: a meta-analysis of randomized controlled trials exploring inter-individual variability. Paula Pinto, Paul Young Tie Yang, Antonio González-Sarrías, Christine Morand, Eileen R. Gibney, Dragan Milenkovic, Geoffrey Istas, Laurent-Emmanuel Monfoulet , Mar Garcia-Aloy, Maria-Teresa García-Conesa, Mireia Urpi-Sarda, Emilie Combet and Ana Rodriguez-Mateos (WG2)
• Polyphenols and platelets function: challenges and strategies in meta-analysis of randomized clinical trials. Pantovic A, Konic-Ristic A., Kroon P., Pinto, P., González-sarrías A.,  de Roos B., Rodríguez-Mateos- A., Gibney ER., Milenkovic D., Morand C., Combet E.

8^th international Conference on Polyphenols and Health, October 3-6,  2017, Quebec city, Canada.
COST Action FA 1408 - POSITIVe An international network to increase knowledge in inter-individual variation in response to consumption of plant food bioactives and determinants involved (Positive network)

1^st International Conference on Food Bioactives and Health, Norwich (UK), 13.9.-15.9, 2016.
Survey of human studies relevant to inter-individual variability in ADME of quercetin. Almeida A.F., Borge G.I., Piskula M., Tudose A., Tudoreanu L., Valentová K., Williamson G., Santos C.N. (WG1)

11^th NuGOweek nutrigenomics of foods , November 08-11, 2014 - Castellammare di Stabia, Italy .
COST Action POSITIVe: interindividual variation in response to consumption of plant food bioactives.Manach C., Milenkovic D., Morand C.

Other oral presentations with COST Acknowledgments

1. Puertas-Martín, V.; Cuevas, C.; Pino, A.; Sabater, G.; San Román, R.; de Pascual-Teresa, S. Protective effect of red berry and cocoa polyphenols against age-related cognitive impairment. Symposium on ‘Nutrition for the Ageing Brain: Moving Towards Clinical Applications. ILSI Europe, Madrid, Spain, 30-31 August, 2018.
2. Valentová K., Křen V.: Bacterial enzymes as a useful tool for the preparation of polyphenolic Phase II metabolite standards, 8th International Conference on Polyphenols and Health ICPH 2017, Quebec (Canada), 3.10.-6.10.2017. Book of abstracts: page 38
3. Valentová K., Havlík J., Kosina P., Hroncová Z., Papoušková B., Křen V., Ulrichová J.: Biotransformation of silymarin flavonolignans by human fecal microflora. 2nd International Conference on Food Bioactives and Health, Lisbon (Portugal), September 26-28, 2018.
4. M.T. García-Conesa. Contrasting in vitro vs. human studies to further understand the molecular effects of plant bioactives: the case of the urolithins against colon cancer. 8th International Conference on Polyphenols and Health, Quebec, Canada, October 3-6, 2017.
5. Koistinen VM, Nordlund E, Katina K, Poutanen K, Aura A-M, Hanhineva K: Non-targeted metabolomics of sourdough fermentation in wheat and rye bread. The Power of Rye Congress, Mariehamn, Finland, June 7–8, 2017
6. Sonia de Pascual Teresa. Methodology used for the evaluation of the health beneficial effects of food components, VII International Conference on Food Science and Technology (1-3 October 2018, Cordoba, Argentina)
7. Sonia de Pascual Teresa. Neurocognitve effect of cocoa. Biological Action of its Polyphenols. Facultad de Ingeniería y Ciencias Agrarias UCA, Buenos Aires, October 2018.
8. S. N. El, S. Karakaya. Encapsulation systems for delivery of anthocyanins for food enrichment applications. International Conference on Food Science and Technology, November 13-15, 2017, Rome, Italy.  
9. Pınar Ercan, Sedef Nehir El. Assessing digestive enzymes inhibitory properties of anthocyanins and procyanidins from some foods.  20th International Conference on Food Function and Bioactive Compounds, January 25-26, 2018. Paris, France. (ITC Grant)
10. Hulya Ilyasoglu Buyukkestelli, Sedef Nehir El. Improving Lutein Bioavailability by Nanotechnology Applications.  20th International Conference on Food Function and Bioactive Compounds, January 25-26, 2018. Paris, France. (ITC Grant)
11. Desmarchelier C. The effect of genetic variations on the bioavailability of phytofluene. Invited conference - COST Eurocaroten - EurocarotenWorkshop - 23-24 October 2018 - Valencia (Spain)
12. Sedef Nehir El, S. Karakaya. Encapsulation systems for delivery of anthocyanins for food enrichment applications. International Conference on Food Science and Technology, November 13-15, 2017, Rome, Italy.

Other posters with COST Acknowledgments

1. Vavříková E., Křenková A., Valentová K., Ježová Ľ., Křen V.: Isoquercitrin Esters with Aliphatic or Aromatic Acids: Enzymatic Preparation and Properties, Biotransformations 2016, Biotransformations for Pharmaceutical and Cosmetic Industry, Warsaw (Poland), 30.6.-2.7.2016. Book of abstracts: page 64, poster P16.
2. Káňová K., Valentová K., Pelantová H., Křenková A., Křen V.: Quercetin-3-O-sulfate and quercetin-4-O-sulfate differ in antioxidant activity, 1st International Conference on Food Bioactives and Health, Norwich (UK), 13.9.-15.9.2016. Book of abstracts: page 174, poster. 
3. Koistinen VM, Nordlund E, Katina K, Lehtonen M, Poutanen K, Aura A-M, Hanhineva K: MS-based analysis of phenolic phytochemicals in rye bran and their microbial metabolites. Food Bioactives & Health, Norwich, UK, September 12–16, 2016, poster presentation.
4. Koistinen VM, Kärkkäinen O Borewicz K, Jokkala J, Micard V, Rosa-Sibakov N, Auriola S, Aura A-M, Smidt H, Hanhineva K: Microbiota contributes to betaine metabolism and is beneficially affected by bran-enriched diet. Food Bioactives & Health, Lisbon, Portugal, September 26–28, 2018, poster presentation.
5. Hülya İlyasoglu Buyukkestelli, Sibel Karakaya, Sedef Nehir El. Double emulsion for anthocyanins delivery: fabrication and in vitro behaviour. 5^th Internatioanl Conference on Foodomics, 10-12 January, Cesena, Italy (Poster presentation)