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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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CIRM-Pathogenic Bacteria / CIRM-BP

Catalog of strains/DNA
Deposit of strains
Boite de Petri d'enterobactéries/Petri dishes enterobacterium - © Inra C. Sligocki

A collection of pathogenic bacteria for medical and veterinary applications and research

Created in 2006, the CIRM-BP is located within the National Institute for Agricultural Researchcentre of Val de Loire inside the mixed research unit working on Infectiology and Public Health "ISP" and associating the François Rabelais University of Tours. The CIRM-BP thus benefits from a rich scientific environment with expertises in the domains of knowledge of pathogenic agents and infection mechanisms knowledge. The main bacteria studied by the Pole of Bacteriology of the ISP unit are BrucellaEscherichia coliMycobacteriumSalmonellaStaphylococcus and Streptococcus.

The CIRM-BP also benefits from collaboration with the neighboring Experimental Infectiology Platform (PFIE) which is the largest French experimental device in infectiology. This platform offers opportunities for experimentation in confined system (A2 and A3) on most livestock or laboratory animals.

The activity of the CIRM-BP is dedicated to the conservation and the distribution of strains of bacterial pathogens* isolated from animals or from humans as well as the distribution of their genomic DNAs. These strains mainly come from INRA collections. To this end, its facilities meet today's strict biosafety standards regarding the pathogenic bacteria of risk groups 2 and 3. The access to pathogenic microorganisms is restricted to laboratories capable of certifying that biosafety and biosecurity measures, suitable for the ordered strains, do exist in their facilities.

To meet the most demanding standards, a quality assurance program was set up which allows the CIRM-BP to be ISO 9001 certified since 2008.

The aims of the CIRM-BP are also to valorize the biodiversity and particularities of these bacterial pathogens by establishing collaborations with academic or industrial scientific partners. 

These collaborations may for example, lead to:

  • the study of new molecular markers describing the distribution of strains within the concerned species or genus,
  • as well as to comparative genomics' studies to highlight the potential specificities of a group of strains belonging to a species (host specificity, repertoire of virulence genes,...)

The CIRM-BP can also act as a partner in scientific projects to guarantee the quality of biological resources.

The access to pathogenic microorganisms is restricted to laboratories capable of certifying that biosafety and biosecurity measures, suitable for the ordered strains, do exist in their facilities.